Thursday, November 28, 2019

RFP Software Breaking Down the Options - The Writers For Hire

RFP SOFTWARE: BREAKING DOWN THE OPTIONS Several of our RFP clients have asked us if there’s any good proposal software out there. Software that can help them make the proposal writing process a bit easier. Software that can help them keep track of deadlines, rules, forms, and updates. Software that makes it easier to manage feedback from multiple reviewers and balance several time-sensitive moving parts. That’s a tall order. But we thought it was a great idea for a blog. We haven’t used a lot of proposal-specific software, so we decided to embark on a little research to learn more about the proposal management software available today. We reached out to several RFP software companies that were all kind enough to provide us with details of their programs and walk us through their best features. 1.Expedience Software Expedience Software’s RFP response package functions as an add-on to Microsoft Office.It allows users to access features directly through Word, via an additional set of menus that appear within the word-processing program itself. This approach has clear advantages.It takes advantage of Word’s status as the most widely used word-processing software in the world, thereby allowing users who are already familiar with the platform to remain in a comfortable environment.Additionally, it piggybacks on Word’s ability to co-operate with other programs in the Office suite, particularly Excel.In short, it requires users to learn a limited set of new menu options and commands rather than an entirely new program, with a different location on the home screen, a different interface, and different internal logic. As Jason Anderson, vice president for sales at Expedience Software, explained: â€Å"Being in Word brings us lots of advantages, mainly that i t’s known.† Sticking to this familiar platform helps users save time, reduce the learning curve and make fewer mistakes along the way, he said. Expedience Software adds new tabs to the Word menu at the top of the screen – namely, Style Palette and Content Portfolio.The latter is likely to be the first destination when generating a new response to RFP, as it allows users to open proposals and access relevant company information and data through the selection of a content portfolio (i.e., a library of stored content from completed proposals and related documents). It lets them search the content portfolio and use the results of the search to add boilerplate text to documents. Additionally, it gives users the ability to add metadata tags to items within the portfolio to facilitate future searches. Style Palette allows users to format proposal documents, using familiar Word features such as style settings, tables and text boxes.It can apply previously used formatting and styles, so that new documents don’t have to be built from scratch. This approach has clear advantages.It takes advantage of Word’s status as the most widely used word-processing software in the world, thereby allowing users who are already familiar with the platform to remain in a comfortable environment.Additionally, it piggybacks on Word’s ability to co-operate with other programs in the Office suite, particularly Excel. In short, it requires users to learn a limited set of new menu options and commands rather than an entirely new program, with a different location on the home screen, a different interface, and different internal logic. As Jason Anderson, vice president for sales at Expedience Software, explained: â€Å"Being in Word brings us lots of advantages, mainly that it’s known.† Sticking to this familiar platform helps users save time, reduce the learning curve and make fewer mistakes along the way, he said. Expedience Software adds new tabs to the Word menu at the top of the screen – namely, Style Palette and Content Portfolio. The latter is likely to be the first destination when generating a new response to RFP, as it allows users to open proposals and access relevant company information and data through the selection of a content portfolio (i.e., a library of stored content from completed proposals and related documents). It lets them search the content portfolio and use the results of the search to add boilerplate text to documents. Additionally, it gives users the ability to add metadata tags to items within the portfolio to facilitate future searches.Style Palette allows users to format proposal documents, using familiar Word features such as style settings, tables and text boxes.It can apply previously used formatting and styles, so that new documents don’t have to be built from scratch. The newest version of Expedience Software’s package also features an Excel Connect tab (not sho wn in the images above). This tab allows users to move easily back and forth between Word and Excel, a handy feature when responding to RFPs that require bidders to submit their responses in spreadsheet format. One drawback of the tie-in with MS Office is that Expedience Software does not have built-in scheduling or calendar capabilities, so it doesn’t give users the ability to set target dates and arrange for automatic reminders of upcoming deadlines.And, since it focuses primarily on document creation and editing, Expedience Software doesn’t offer as many project management as other software. But Expedience Software does feature an intriguing approach to security and user access. Most of the providers we spoke with used a full licensing system that required each user within a company to have an individual license to access the program. But Anderson explained that Expedience Software issues licenses only to users who need to access every part of the content portfolio. License holders can then grant outside experts and consultants limited access to basic viewing and editing functions without the need to acquire additional licenses, he explained. â€Å"Most other software wont let you control access to content in this way, but we do,† he said. Anderson also stressed that license holders had the ability to prevent unlicensed users from accessing every part of the company’s library. â€Å"You can restrict authorship,† he said, explaining that this option preserved the security of company records while ensuring that lower-level employees and outside consultants could still view and edit proposal documents as necessary. He further noted that these security provisions allowed managers to protect confidential information without setting up additional storage infrastructure. License holders can restrict authorship to documents on existing company servers or any other storage solution, he said. â€Å"If there’s a firewall, it can be behind that. It can be on a network drive [or] in the cloud,† he said. The bottom line: Expedience Software provides advanced document-management options in a setting that is both familiar and easy to access. Main pros: Based on familiar Word platform and has a low learning curveTies directly into ExcelMain cons: No scheduling or calendar features Few project management features 2.Qwilr Qwilr is quite different from Expedience Software. This is not just because it is a stand-alone program with no explicit link to existing platforms, but also because it aims to turn out a different type of product. Responses to RFPs typically follow one of two formats: Word-type documents that describe a given company’s ability to provide goods and/or services, as well as its compliance with requirements Spreadsheets that contain the same type of data and information in a pre-formatted, Excel-type format By contrast, Qwilr allows users to generate a dynamic response that bears more resemblance to a web page than to a stack of paper. Finished Qwilr products are web-based and have website-like elements such as hyperlinks, video content and online quote acceptance. Additionally, they can be built, edited and viewed on smartphones, tablets and other mobile devices. The software appears to be easy to navigate, with a straightforward, point-and-click interface. â€Å"In terms of ease of use, we’re up there. The software is even pleasant to use,† said Jomar Gomez, a sales and customer success representative for Qwilr. Moreover, he said, the end product is easy to navigate, â€Å"as it’s more like a web page with design elements.† Qwilr’s main focus is on this type of dynamic presentation. But users can also generate RFP responses in several formats, including text, and can save files as PDFs. Additionally, Qwilr makes plenty of design and graphic elements available to users seeking to craft dynamic responses.It incl udes multiple pre-set templates, each with a different look and feel, and also lets users access a library of stock photos. The software also offers a built-in quote acceptance tool that allows for a rapid response from contracting organizations.This easy-to-use tool features sliders that can be activated with the click of a mouse or the tap of a finger. Another handy tool is the Analytics feature, which helps users keep track of the progress of a project, from the creation of the initial document to responses from contracting organizations Despite its forward-looking features, Qwilr does not lose sight of the fact that users need more than attractive graphics and design. It gives users the ability to create and access a library of boilerplate texts, and its Clone feature streamlines the process of using previous documents as a model for new responses. Qwilr uses a standard licensing model, with each individual user required to obtain a license. It also includes security features su ch as Block, which restricts access to and editing capabilities, making it a good fit for companies that bring in outside consultants or experts when drafting proposals. There are some downsides to this software, however: Qwilr does not tie directly into Excel, so it offers no advantages to users responding to RFPs in spreadsheet format. It does not appear to have a calendar function, though it does have an audit trail that lays out the timeline for each project. The bottom line: Qwilr allows users to craft proposals that will stand out from the crowd. Main pros: delivers visually striking content, includes useful toolsMain cons: doesn’t help with spreadsheet RFPs, no scheduling or calendar features, more suited to smaller companies that can present proposals in person 3.Loopio and RFPIO Both Loopio and RFPIO allow companies to compile and draw on examples of past work, thereby simplifying tasks such as retrieving standard boilerplate text or duplicating existing formats.B ut they each offer unique takes on RFP response software.Loopio and RFPIO do not piggyback on MS Office like Expedience Software; and they don’t emphasize web-style, graphics-focused content like Qwilr. Instead, these stand-alone packages bear a strong resemblance to project management systems, as both have dashboards and group projects into folders. Their folders and menus help companies to build on previous proposals and to compile boilerplate text, as both employ templates and metadata tags, as well as document and answer libraries. Additionally, both are cloud-based platforms that use a standard licensing model. Both can be used on mobile devices as well as PCs. There are differences between the two, though. The most noticeable of these is that RFPIO appears to have a wider range of capabilities than Loopio. For example, RFPIO does not require users to work from templates, although it does offer them that option. It allows users to fill out a form with the relevant infor mation (or with a command to retrieve specific information from the content library) and then generates a proposal on its own. RFPIO also offers a predictive text function based on artificial intelligence (AI) capabilities. This reduces the time needed to search for and retrieve relevant information, said Chris Pulley, an account executive at RFPIO. â€Å"There’s not even a need to cut and paste. That’s a huge component of the software,† he said. â€Å"RFPIO automatically saves answers to questions. It will also suggest answers for you using key words, without any prompting. [This feature] is a key way to save time.† Additionally, the program allows users to import questionnaires and MS Office files with only one click of the mouse. As such, it facilitates replies to spreadsheet-based RFPs while also streamlining the process of drawing on document files in Word or Excel format. Both types of software allow companies to customize access levels for multipl e users in order to guard confidentiality. However, Loopio only grants access to license holders, which means that companies using outside experts or consultants must obtain an additional license, explained Allison Russell, a sales development representative for the company. â€Å"The software is designed to serve a group of people collaborating and working on the same response toward a common goal, but it keeps confidential information secure,† she said. â€Å"We have different settings for that, and they’re up to the discretion of the user. The settings can be made different for each license user.† RFPIO, by contrast, gives users the option of granting outside consultants and experts access to content portfolios without additional licenses. It also lets users set custom security levels to ensure that these contributors can access the information they need and no more. â€Å"There are different levels of access – administrator, member, and guest,† Pulley said. â€Å"The guest feature lets any employee be set up as a member of the team working on the response.† RFPIO and Loopio also differ significantly with respect to scheduling oversight. On this front, RFPIO clearly comes out ahead, as it includes a calendar function that allows users to set specific deadlines and arrange for automatic reminders. And as Pulley emphasized, these notices and reminders are not just for major projects involving an entire team, but also for sub-tasks, assignments and questions directed to individuals, smaller groups and outside contributors. Loopio, by contrast, follows Expedience Software and Qwilr in offering few options for scheduling. Russell did note, though, that the package included useful features for users seeking to comply with deadlines. â€Å"Project managers can have control over notifications,† she said. â€Å"They can send prompts and reminders to team members, using Loopio to send out emails with their message.â⠂¬  The bottom line: RFPIO and Loopio provide users the ability to generate and manage proposals in a project-management setting. RFPIO pros: calendar feature, tracks project progress in a manner similar to Qwilr’s Analytics tool, easy integration with MS Office files RFPIO cons: smaller companies may not need or use all features Loopio pros: offers consistent branding through easy formatting options, builds strong library of boilerplate text and answers to previous questions Loopio cons: no scheduling or calendar features, does not have same level of integration with MS Office files Making the Decision Of the two cloud-based software packages reviewed here, RFPIO appears to be a better option than Loopio. While the two systems are similar in visual presentation and basic functionality, the former gives users more options for managing content and access. Among the other two, there is no obvious winner. Expedience Software offers the lowest learning curve and the best integration with MS Office, but it is not an ideal platform for project management or scheduling. One online review[i] also indicates that it works best for users who are already familiar with Word’s most advanced options. For its part, Qwilr delivers the most attractive responses for companies seeking to stand out from their text-focused competitors, but its finished products will not satisfy all potential customers – especially large contracting organizations that require proposals to be submitted in the form of a spreadsheet. Instead, its web-based proposals probably pack the biggest visual punch in small, face-to-face settings. The choice of RFP response package would seem to hinge, then, on the individual needs of potential buyers. Companies seeking to simplify and improve the RFP response process should, therefore, strive for a match between their resources and the software’s capabilities.Tweet this [i] 1. https://www.capterra.com/p/141108/Expedience-Software-Suite/#reviews: Scroll down to review by Crawford R.

Monday, November 25, 2019

Phosphorylation and How It Works

Phosphorylation and How It Works Phosphorylation is the chemical addition of a phosphoryl group (PO3-) to an organic molecule. The removal of a phosphoryl group is called dephosphorylation. Both phosphorylation and dephosphorylation are carried out by enzymes (e.g., kinases, phosphotransferases). Phosphorylation is important in the fields of biochemistry and molecular biology because its a key reaction in protein and enzyme function, sugar metabolism, and energy storage and release. Purposes of Phosphorylation Phosphorylation plays a critical regulatory role in cells. Its functions  include: Important for glycolysisUsed for protein-protein interactionUsed in protein degradationRegulates enzyme inhibitionMaintains homeostasis by regulating energy-requiring chemical reactions Types of Phosphorylation Many types of molecules can undergo phosphorylation and dephosphorylation. Three of the most important types of phosphorylation are glucose phosphorylation, protein phosphorylation, and oxidative phosphorylation. Glucose Phosphorylation Glucose and other sugars are often phosphorylated as the first step of their catabolism. For example, the first step of glycolysis of D-glucose is its conversion into D-glucose-6-phosphate. Glucose is a small molecule that readily permeates cells. Phosphorylation forms a larger molecule that cant easily enter tissue. So, phosphorylation is critical  for regulating blood glucose concentration. Glucose concentration, in turn, is directly related to glycogen formation. Glucose phosphorylation is also linked to cardiac growth. Protein Phosphorylation Phoebus Levene at the Rockefeller Institute for Medical Research was the first to identify a phosphorylated protein (phosvitin) in 1906, but enzymatic phosphorylation of proteins wasnt described until the 1930s. Protein phosphorylation occurs when the phosphoryl group is added to an amino acid. Usually, the amino acid is serine, although phosphorylation also occurs on threonine and tyrosine in eukaryotes and histidine in prokaryotes. This is an esterification reaction where a phosphate group reacts with the hydroxyl (-OH) group of a serine, threonine, or tyrosine side chain. The enzyme protein kinase covalently binds a phosphate group to the amino acid. The precise mechanism differs somewhat between prokaryotes and eukaryotes. The best-studied forms of phosphorylation are posttranslational modifications (PTM), which means the proteins are phosphorylated after translation from an RNA template. The reverse reaction, dephosphorylation, is catalyzed by protein phosphatases. An important example of protein phosphorylation is the phosphorylation of histones. In eukaryotes, DNA is associated with histone proteins to form chromatin. Histone phosphorylation modifies the structure of chromatin and alters its protein-protein and DNA-protein interactions. Usually, phosphorylation occurs when DNA is damaged, opening up space around broken DNA so that repair mechanisms can do their work. In addition to its importance in DNA repair, protein phosphorylation plays a key role in metabolism and signaling pathways. Oxidative Phosphorylation Oxidative phosphorylation is how a cell stores and releases chemical energy. In a eukaryotic cell, the reactions occur within the mitochondria. Oxidative phosphorylation consists of the reactions of the electron transport chain and those of chemiosmosis. In summary, redox reaction pass electrons from proteins and other molecules along the electron transport chain in the inner membrane of the mitochondria, releasing energy that is used to make adenosine triphosphate (ATP) in chemiosmosis. In this process, NADH and FADH2 deliver  electrons to the electron transport chain. Electrons move from higher energy to lower energy as they progress along the chain, releasing energy along the way. Part of this energy goes to pumping hydrogen ions (H) to form an electrochemical gradient. At the end of the chain, electrons are transferred to oxygen, which bond with H to form water. H ions supply the energy for ATP synthase to synthesize ATP. When ATP is dephosphorylated, cleaving the phosphate group releases energy in a form the cell can use. Adenosine is not the only base that undergoes phosphorylation to form AMP, ADP, and ATP. For example, guanosine may also form GMP, GDP, and GTP. Detecting Phosphorylation Whether or not a molecule has been phosphorylated can be detected using antibodies, electrophoresis, or mass spectrometry. However, identifying and characterizing phosphorylation sites is difficult. Isotope labeling is often used, in conjunction with fluorescence, electrophoresis, and immunoassays. Sources Kresge, Nicole; Simoni, Robert D.; Hill, Robert L. (2011-01-21). The Process of Reversible Phosphorylation: the Work of Edmond H. Fischer. Journal of Biological Chemistry. 286 (3).Sharma, Saumya; Guthrie, Patrick H.; Chan, Suzanne S.; Haq, Syed; Taegtmeyer, Heinrich (2007-10-01). Glucose Phosphorylation Is Required for Insulin-Dependent mTOR Signalling in the Heart. Cardiovascular Research. 76 (1): 71–80.

Thursday, November 21, 2019

The Child Left Behind Essay Example | Topics and Well Written Essays - 1250 words

The Child Left Behind - Essay Example The increased emphasis that the NCLB Act places on the subjects of math and reading undermines the importance of all other subjects that are either equally or more important for the inculcation of the required academic and professional skills in the children. The goals that schools in conventional practice set for the students are not limited to the inculcation of general reading and math skills but also extend to the development of appropriate critical thinking skills, emotional intelligence, conflict resolution, self-discipline and the health and safety habits in the students. When there are sanctions to threaten the schools just in case they do not meet their expectations with respect to one particular goal, the schools are bound to have their attention diverted from the rest of the goals that are equally or more important than that one goal. Having been educated in the NCLB culture, my knowledge of or skill in arts, science, music, social studies and exercises is close to negligi ble. This is so because my teachers could not afford to spend time on such subjects because they feared they would have to face the most unfavorable consequences if they did. The problem of goal distortion has been recognized at various levels. Even the former education assistant secretaries Diane Ravitch and Chester Finn have realized the negative impact of overemphasis on one area upon the others. They said, â€Å"[If NCLB continues,] rich kids will study philosophy and art, music and history, while their poor peers fill in bubbles on test sheets. The lucky few will spawn the next generation of tycoons, political leaders, inventors, authors, artists and entrepreneurs. The less lucky masses will see narrower opportunities† (Ravitch and Finn cited in Rothstein). NCLB assesses the students’ learning from the annual test which can in many ways be quite misleading. On certain days in the year, a child’s performance may be outclass while on others, his/her performan ce may be below average. It is not just the studies that are there in a child’s life after all. The child may be upset because of some familial reason. The child may not be feeling well on the exam day. There can be hundreds of reasons for the declined performance on certain days. Taking this into consideration, there is dire need for multiple retesting in order to have an accurate assessment of the child’s learning. In addition to that, the number of subgroups in a school also has an impact upon the child’s academic performance. The margin of error for the academic achievement of a subgroup is enhanced because of the smaller size of the subgroups in a school in comparison to a full-grade cohort. Accountability becomes increasingly inaccurate as the subgroups in a school integrate in increased numbers. Students cannot be sure that all students are proficient at the challenging level as is expected of them even if the math and the reading are paid excessive atten tion towards. The variability in human nature and skills prevents such proficiency irrespective of the disparities originating in the socioeconomic statuses of the students. The normal intelligence quotient (IQ) of the humans that accounts for about 66.66 per cent of the total human population starts from 85 and ends at 115 (Rothstein). What the

Wednesday, November 20, 2019

Gene Essay Example | Topics and Well Written Essays - 2000 words

Gene - Essay Example will be joined with plasmids cut by the same restriction enzymes through their compatible and matching sticky ends, producing a recombinant DNA molecule, which will be inserted to an appropriate host cell. Plasmids can either be bacterial, viral, bacterial artificial chromosomes, yeast artificial chromosomes, or artificial cosmids, depending on the host organism of choice. Plasmids can also be classified based on its function, such that there is a certain set of vectors that can be used if the goal of the experiment is to only propagate the gene, as is the case for this particular study. However, vectors that allow expression of particular gene into the corresponding protein are also available as well. The growth in the population of host cells containing the recombinant DNA molecule will also result to the replication of the gene clone. As added optimizing measure, aside from the G6Pase sequence and restriction sites, the vector also contains resistance genes against antibiotics. Thus, those that do not have the recombinant DNA molecule will be killed by antibiotics, allowing the transformed cells to flourish better. When the clone is needed for further analysis, it can easily be extracted out of the cell (U.S. Department of Energy Genome Program, 2009). It is important to note that the mouse genetic material is very similar to that of humans. Thus, a known mouse G6Pase sequence can be used in hybridization as the heterologous probe in identifying the human G6Pase (McClean, 1997). How will this work? Briefly, human DNA sample will be treated with restriction enzymes to cut the long strands into smaller fragments. After doing so, the treated extract will be run through gel electrophoresis to separate the smaller fragments by weight. Then, using the mouse gene attached to a dye as heterologous probe, the strand which contains the human G6Pase will be detected and isolated. Copies of this isolated gene can be amplified through polymerase chain reaction (PCR).

Monday, November 18, 2019

Emily Islation Essay Example | Topics and Well Written Essays - 1250 words

Emily Islation - Essay Example The story explains that Emily got isolated and insane because of her Father which led her to kill her love and later die in agony.( Thesis). Emily had lived with her Father till he died and she never wanted to accept that she lost her father. As per (Fang 18-24) â€Å" In â€Å"A Rose for Emily†, Emily is such a tragic figure who forever lives under her father’s domination, even after his death. But her insanity started with her father’s death and went on to escalate later in life†. Her father never allowed anyone to court Emily and he contributed to her isolation. Later she got used to the lonely lifestyle and lived in isolation. After, her Father’s death she embraced isolation to lighten up her life. For example, she did not even take time to throw out the people who come to collect tax but order to throw them out. She also did not hold a civil conversation with them. She also did not communicate with her community and never went out. This in a way supported her. Because of her isolated life people thought of her as a weak women but she was strong inside. She could kill Homer and pret end to be naà ¯ve and isolation allowed her to keep her secrets. The root cause of all her problems had been her father. She is isolated from her city, relatives and people around her. Her alienation from love has led her to insanity. Emil’s isolation is evident because after her Father death, she felt deserted and hid from the society and embraced loneliness. As per ( Faulkner 129) â€Å"After her fathers death she went out very little; after her sweetheart went away, people hardly saw her at all†. Emily is a character who did not want to confront the reality. She lives in a fantasy world and where death has no meaning. Emily refused to accept that the life around her is changing and she wants to fondle the memories of her fast forgetting the present. After her father’s death she did not go out much and her

Saturday, November 16, 2019

Model Of Nursing And Orems Self Care Model Nursing Essay

Model Of Nursing And Orems Self Care Model Nursing Essay Salvage (2006) reports the RLT model is based on what is considered as twelve activities of living. The model determines that physical/biological, psychological, sociocultural, environmental and politicoeconomical factors all influence the way in which an individual performs these activities of living (Salvage, 2006). Healy and Timmins (2003) further add that activities of living are one of five main components that are all interconnected. Progression along the lifespan, the dependence/independence continuum, factors influencing the activities of living and the individuality in living completing the final four components. They state the model is one that focuses on the patient as an individual engaged in living throughout a lifespan and moving from dependence to independence according to age, circumstances and environment (Healy Timmins, 2003, p. 792). Healy and Timmins (2003) identify the model is used to identify a patients abilities in each of the twelve activities of living and use this data as a guide to develop an individualised care plan. Meleis (2012) defines Orems framework as one that identifies patients needs and the resulting nursing intervention necessary to enhance self-care. Johnson and Webber (2010) explain Orems Model has three interrelated concepts theory of self-care, theory of self-care deficit and theory of nursing systems. According to Orem, people require assistance when their ability to meet their own self-care needs becomes compromised (Horan, 2004). Orem identifies three categories of self-care common to all people, believing when an individual is unable to meet these needs a self-care deficit occurs (Berman et al, 2012; Fitzpatrick Whall, 2005). Orems model assesses a patients self-care ability to determine the deficit in meeting their own care. Once the deficit is established, one of five methods can be implemented to meet the patients self-care needs. Depending on the patients abilities to perform their own self-care, one of three nursing systems is utilized to meet the needs of the patient (Be rman et al, 2012). Nurses have a responsibility to consider legal and ethical issues that need to be employed when performing health assessments. Legal issues, according to Berman et al (2012) include consent, confidentiality, duty of care and negligence whilst ethical issues include non-maleficence, beneficence, respect for autonomy and justice. Otherwise known as the four principles of bioethics (Atkins, Britton de Lacey, 2011, p. 88). The Australian Nursing and Midwifery Council [ANMC] have developed codes and guidelines that are a minimum standard of practice that a nurse is expected to maintain. When performing health assessments nurses must perform within their scope of practice which is based on education, knowledge, competency, extent of experience and lawful authority (ANMC, 2008). Atkins, Britton and de Lacey (2011) identify the position of power a nurse holds over a patient because of their inability to meet certain self-care needs and their reliance on the assistance of a nurse. They describe the relationship that exists between nurse and patient as a fiduciary relationship (Atkins, Britton de Lacey, 2011, p. 82). Central to this relationship is cooperation with the patient, with him/her an active member of the decision making process (Atkins, Britton de Lacey, 2011). It is recognised that the nurse has technical knowledge and expert advice however lacks sufficient knowledge and authority over a patients life. Therefore the nurse lacks the expertise to make significant decisions without the patients consent. A patient must consent to any health assessment being performed, however, the nurse first must provide sufficient and relevant information about the assessment being undertaken. Any framework implemented in the nursing environment will always come with strengths and limitations. Whilst not practising the Self-Care Model as Orem packaged it, Johnson and Webber (2010) state nurses have embraced the logic of self-care as therapeutic. This has resulted in them focusing their care focused towards helping patients meet their self-care needs rather than performing these for them. This promotes patient independence and maximizes nursing resource. Nurses have integrated principles of the model into diverse practice settings including different cultures and the world. Horan (2004) presented the use of Orems model in the field of intellectual disability and initially believed the model was too complex for successful application in this arena. His view changed when he saw the benefit the model provided to cater for individuals, with total care for one patient or just education and support for another. Meleis (2012) highlights the versality of the model with its use in preoperative and postoperative care, psychiatric, palliative and HIV patient care, ranging from geriatric patients to adolescents and children. Fitzpatrick and Whall (2005) identify the model is relevant, noting its implementation in many health care institutions. Ths suggesting the model is flexible and adaptable to form an individual care plan that will meet an array of patient needs. Orems model provides a framework for intervention and in her own words states self-care deficit theory of nursing will fit into any nursing situation because it is a general theory, that is, an explanat ion of what is common to all nursing situations, not just an explanation of an individual situation (Meleis, 2012, p. 208). Irrespective of these strengths, Johnson and Webber (2010) believe Orems model is detailed and burdened with complicated language. Meleis (2012) supports their idea, suggesting the model is ambiguous, lacks clarity and can result in misinterpretation. Fitzpatrick and Whall (2005) state the theory can be viewed as culturally biased due to the fact it relies on principles such as autonomy, self-determinism and self-reliance. Principles that are not adopted in all cultures. Orems model addresses how nursing actions function to enhance health therefore being a valuable tool in the lives of those whose ability to self-care is thwarted. However, Fitzpatrick and Whall (2005) argue it may not make the same impact in health prevention care and promoting health. They claim its focus on self-care deficits resulting from health problems excludes a health promotion focus. Meleis (2012) supports this claim concluding that as nursing shifts to more community focus, the model will need to be supplemented with focus on health prevention and promotion care. Johnson and Webber (2010) identify that nursing would benefit from principles from a range of frameworks to enhance holistic assessment rather than limiting its practice to the boundaries of one single framework. This essay has discussed RLT Model of Nursing and Orems Self-Care Model as health care frameworks that can be used when collecting heath assessment data. It outlined legal and ethical issues underpinning the nurse-patient relationship and how these must direct any interaction with the patient when conducting health assessment. Finally, it brought attention to the strengths and weaknesses when using Orems Self-Care Model, evidence showing whilst there are limitations to the model, there are attributes that make it valuable. Whilst the clarity of the model seemed questionable due to language used, the ability the model has to cater for patients with varying capacities proved it flexible and adaptable, encouraging and promoting patient independence.

Wednesday, November 13, 2019

No Universal Truth Essay -- Philosophy Religion Essays

No Universal Truth Hume wrote, â€Å"be a philosopher; but, amidst all your philosophy, be still a man,† (qtd. in Jones 351). This statement strikes me more than all others, written by Hume or any of the philosophers from W. T. Jones’ Hobbes to Hume. It demonstrates to me that even after all of the inquisition towards what and how we can know anything, and the very methodical ways in which Hume is reputed to examine these things, he realizes that nothing is truly certain and begins to lean towards a pragmatic and radically empirical point of view. It is, therefore, also my conclusion that, as much as we may aspire to find the universal, indubitable, and objective truth, none of it can be proven to be universal, indubitable, and objective. In support of this view—the â€Å"abandonment of the quest for certainty, acceptance of provisional solutions as long as they work, and readiness to discard them when changing conditions make them no longer appropriate†Ã¢â‚¬â€I will endeavor to briefly examine substance, the self, and the presumed necessary connection of ideas or events (Jones 349). By applying his own empirical criterion of meaning to the examination of such a notably philosophical concept as substance, Hume flat out disposes of the entire notion itself. As has been formerly introduced by Descartes, substance is a fluctuating thing that takes on the same meaning as is best described by that certain je ne sais quoi. It is that certain something you just can’t put your finger on, and â€Å"by substance, we can understand nothing else than a thing which so exists that it needs no other thing in order to exist,â€Å" (qtd. in Jones 174-175). Descartes naturally takes this thing to be God, but never questions the meaning of God or substance a... ... and finally removes reasons for the existence of any connection between any of the ideas which we as a species have always held as being related. Hume also refutes any reason to believe in the existence of an external world, or a world without us, which has not been discussed here. In the end, there is really no reason to believe in the existence of existence, if Hume’s deductions are to be taken quite so seriously. Of course, if that were to be done, none could live as they do. Since Hume himself is concerned with a philosophy that concerns the everyday individual, not even he can truly accept that nothing exists. It is when he reaches this point himself that he realizes one can â€Å"be a philosopher; but, amidst all your philosophy, be still a man,† (qtd. in Jones 351). Works Cited Jones, W. T. Hobbes to Hume. 2nd edition. Fort Worth: Harcourt, 1980.

Monday, November 11, 2019

On The Progress Of A University Education Essay

I ‘ve been appointed as Director of concern school services which deal with Numberss of different organisations in different parts of North America. Ottawa Business School is an international school which has excelled in many assorted states and parts for decennaries now. It is considered one of the top universities in North America and is regarded as one of the universe ‘s most extremely concern schools. Its MBA plan is often ranked among the planetary top. Ottawa Business School Teachs postgraduate programmes in finance and direction for experient concern executives, Masters in Finance, Masters in Management, and PhD. It was established in 1975 as portion of bing universities such as Toronto Business Schools every bit good as Montreal Academy for Business Administration. It has close coactions with the nearby Montreal Academy and the Modern Language Centre at Ottawa ‘s College Institute. The admittances procedure at OBS is extremely selective ; doing it is one of the most competitory concern schools in the universe. The School has over 10,000 pupils in more than 30 different metropoliss and provinces. One of the most of import tools used in Ottawa Business Schools is the communicating between the different subdivisions amongst the assorted metropoliss and the communicating used between the staff members and pupils. Some agencies of communicating used in a topographic point like OBS is face to confront communicating, electronic mails, facsimile, telephones, meetings ( verbal and non-verbal communicating ) etc. OBS has about 620 educated and experienced instructors and professors with assorted backgrounds in all subdivisions. Most of the staff members have either a Masters or PhD Degree with adequate experience to learn in any concern installation. I am really delighted to be in this fantastic place. However, as clip passed, I began to detect that communicating between the fellow pupils and staff members was non every bit coherent as should be. I had to take immediate action and expression into this job. For this university to remain on the top and for the pupils and module to be in a good structured environment, communicating needed to better. Communication is critical for any organisation to win. Communication is an of import portion of instruction because the pupils have to be able to understand the message that the instructor is seeking to convey. However, I have noticed some physical barriers that have affected this. These barriers included the deficiency of listening accomplishments that the staff and pupils conveyed, and the deficiency of feedback given by the pupils to demo their apprehension. Effective hearing is one of the most of import factors in schoolroom communicating. However, in Ottawa Business School, this is a beginning of communicating job. Peoples frequently fall short hearing carefully. Besides, when people are in a dissension, they frequently ponder more on what they are traveling to state in answer to their opposition ‘s statement, comparatively than listening to their opposition ‘s words with full attending. For illustration, when a pupil and a instructor get into a small statement about school issues, one of the two might be excessively upset to even listen to what the other has to state. The consequence, once more, is misinterpretations, and frequently gratuitous rise of a struggle. Taking the clip to deeply seek the jobs at Ottawa Business Schools, I was really disquieted when I noticed that a deficiency of feedback prevailed in the schoolrooms. Working 25 old ages in the concern universe, I knew how of import it is for feedback to be given. It is indispensable as incorrect or deficiency of feedback can do many lacks in all the types and ways of communicating in general. Feedback is critical for the transmitter to be certain that the receiving system decoded his or her message in the right manner. Nevertheless, I was shocked to see the pupil ‘s engagement in some of the categories. No inquiries were being asked, by both the pupils and instructors and even when asked by instructors, the pupils did non reply. How did the instructors know that their pupils to the full understood what was being said or asked? Sadly, at that point, it besides came to my attending that, I, as the Director of this university, have non taken the clip to prosecute with my fellow pupils and cognize or be informed if they believe some of the ordinances should be altered. This was besides a cause of deficiency of feedback and communicating. These physical barriers were non the lone grounds that broke down the flow of effectual communicating in the lower degree of the organisation. A large portion of it was due to cultural barriers. Speakers frequently are non clear about what they imply, which assures that what they say will be ill-defined as good. Even when people are familiar to what they mean, they frequently do non declare it every bit clearly as they should. Furthermore, people frequently get baffled about other people ‘s messages. This is peculiarly common when people from diverse civilizations try to pass on, which may happen repeatedly in topographic points such as schools, organisations, or even assemblages. Ottawa Business School is an international society which includes a figure of different people with different nationalities and linguistic communications. I have noticed that since the civilizations are diverse here, it is simple for the same statement to denote one thing to one individual and somethi ng different to person else. Teachers are non precisely cognizant of this. For illustration, go throughing an point to person with one manus is considered extremely rude in Japan while it is acceptable in the Eastern Countries. Gestures can besides be misinterpreted. For case the O.K gesture in America and England is given to intend everything is all right, while in France it is considered an abuse. Even though it might non look as an contemptuous facet, some pupils are really cultural and this can pique them. I besides became cognizant that both instructors and pupils have predisposed ideas about behaviour based on people ‘s civilization. One of my staff members has been unjust to a group of pupils from China. They have been handling them in a unit of ammunition and biased mode. When these Chinese pupils ask inquiries in category, they do non acquire prompt replies. This has besides influenced the other pupils to handle the group of Chinese pupils in a disrespectful manner in and outside of category. The concluding barrier that came to my concern was the behavior barriers. These included the verbal and non-verbal methods. Several staff members displayed a great trade of attitude towards their pupils. They did non to the full listen to them and interrupted them while talking. When attitude got in the manner of communicating, people declined to listen to one another. Teachers have besides brought all kinds of issues to work that had nil to make with their occupation. These included personal problems, household issues and other jobs. These quandaries have put instructors under huge emphasis and due to this emphasis, I have noticed that the instructors have non been learning or listening good and have been less effectual communicators. It was my duty to get the better of these communicating jobs. I took the clip to lucubrate on each of these state of affairss and I eventually came up with sensible declarations. I held a meeting with the staff members to put some regulations and ordinances. It was really indispensable for the instructors to cognize that listening plays a really of import portion in the instruction of the fellow pupils. I made it clear to my staff members that active hearing was the chief method to get the better of the listening barrier. Active hearing is an organized manner of listening and reacting to others and concentrating full attending on the talker. When instructors interrupt the talker before allowing them finish, they are basically stating that they do n't value what they are stating. This can do pupils experience that their sentiments do non count and non take part in category. I made it clear that instructors should alter their methods in category and do certain that they respond and eng age with the pupils to demo that they are efficaciously listening. This would besides get the better of the deficiency of feedback displayed in category. Teachers should do certain that they are often inquiring inquiries and having replies. It is up to them to do certain that the pupils understand the topic. They may look into for pupils organic structure languages, manus gestures, etc. Ottawa Business School is one of the top universities in the universe. If the cultural barriers were non overcome, this university would hold a bad image to all. It was critical for the staff members to esteem other ‘s cultural and beliefs. Teachers should be proactive when nearing a new civilization. They should esteem their background. It is besides necessary to measure people on an single footing. It is of import to hedge judgement, avoid misguided beliefs, narrow positions, and immature feedbacks. Any staff member who can non accept these conditions will instantly be fired. The concluding barrier that I had to work upon to get the better of was the behavior barrier. I understand if a instructor comes to work disquieted or personally bothered by something one time or perchance twice. However, they should take duty and set their feelings aside for the twenty-four hours or try to command them. An disquieted individual tends to disregard what others are stating and are unable to show thoughts efficaciously. It was my responsibility to inform the staff about this so it does non go on once more. Taking the clip to measure the advancement of my university, I came upon the different barriers that have affected and reduced effectual communicating between the pupils and staff members. By taking action to get the better of these jobs, Ottawa Business School will hold a better environment for all. Students do non hold to be concerned about instructors non listening to them any longer, or handling them in a unit of ammunition mode or acting rough in category. Hopefully, pupils will now be more engaged in the assorted treatments and activities in category and communicate good with their schoolmates and staff members.

Friday, November 8, 2019

Stonewall Jackson essays

Stonewall Jackson essays On January 21, 1824, a baby would soon become an ambitious man. That man, though, will soon be in the U.S. Military Academy at West Point, New York. This man is Stonewall Jackson or Thomas Jonathon Jackson (his real name). When he first got to the Academy he looked awkward, only carrying two saddlebags and wearing homespun clothing. Even though he looked awkward, people saw him and could tell he was here to stay. Staying was not easy for Jackson. He was ready for military life, but had trouble with the academics. Every night he piled his grate full of coal and studied till it went out. Finally that helped, when he graduated he was seventeenth of fifty-nine compared to last of ninety-two who made it to enter. Though the academics were hard for him at the Academy, his schooling (in his childhood) were limited to classes taught by traveling teachers. He could only read, write, and do a little arithmetic. Also, he taught for a few years and got paid $5.64. That was one of the only good things in his childhood. Other than that it was very sad. To start this whole thing off, in 1826, his sister and father, died from typhoid fever when Tom was only two. Though, the very next day, after his fathers death, Laura was born, his younger sister. His mother tried to run the house, but couldnt do it by herself. So she married Blake B. Woodson. Even that couldnt stop what was going to happen next. While she was pregnant with her fifth child, her health began to decline. She then sent he and Laura to live with relatives. Shortly after, she died. He had to go spend time with his Uncle Brake. He hated it there, but needed money so he was serving legal papers on people and collecting bad depts. But Tom was an ambitious lad; he knew that he needed an education if he wanted to make something of himself. When he had an opportunity to apply to the U.S. Military Academy at West Poin ...

Wednesday, November 6, 2019

Transcription vs. Translation

Transcription vs. Translation Evolution, or the change in species over time, is driven by the process of natural selection. In order for natural selection to work, individuals within a population of a species must have differences within the traits they express. Individuals with the desirable traits and   for their environment will survive long enough to reproduce and pass down the genes that code for those characteristics to their offspring. Individuals that are deemed â€Å"unfit† for their environment will die before they are able to pass down those undesirable genes to the next generation. Over time, only the genes that code for the desirable adaptation will be found in the gene pool. The availability of these traits are dependent upon gene expression. Gene expression is made possible by the proteins that are made by cells during   and translation. Since genes are coded for in the DNA and the DNA is transcribed and translated into proteins, the expression of the genes are controlled by which portions of the DNA get copied and made into the proteins. Transcription The first step of gene expression is called transcription. Transcription is creation of a  messenger RNA molecule that is the complement of a single strand of DNA. Free floating RNA nucleotides get matched up to the DNA following the base pairing rules. In transcription, adenine is paired with uracil in RNA and guanine is paired with cytosine. The RNA polymerase molecule puts the messenger RNA nucleotide sequence in the correct order and binds them together. It is also the enzyme that is responsible for checking for mistakes or mutations in the sequence. Following transcription, the messenger RNA molecule is processed through a process called RNA splicing. Parts of the messenger RNA that do not code for the protein that needs to be expressed are cut out and the pieces are spliced back together. Additional protective caps and tails are added to the messenger RNA at this time as well. Alternative splicing can be done to the RNA to make a single strand of messenger RNA able to produce many different genes. Scientists believe this is how adaptations can occur without mutations happening at the molecular level. Now that the messenger RNA is fully processed, it can leave the nucleus through the nuclear pores within the nuclear envelope and proceed to the cytoplasm where it will meet up with a ribosome and undergo translation. This second part of gene expression is where the actual polypeptide that will eventually become the expressed protein is made. In translation, the messenger RNA gets sandwiched between the large and small subunits of the ribosome. Transfer RNA will bring over the correct amino acid to the ribosome and messenger RNA complex. The transfer RNA recognizes the messenger RNA codon, or three nucleotide sequence, by matching up its own anit-codon complement and binding to the messenger RNA strand. The ribosome moves to allow another transfer RNA to bind and the amino acids from these transfer RNA create a peptide bond between them and severing the bond between the amino acid and the transfer RNA. The ribosome moves again and the now free transfer RNA can go find another amino acid and be reused. This process continues until the ribosome reaches a â€Å"stop† codon and at that point, the polypeptide chain and the messenger RNA are released from the ribosome. The ribosome and messenger RNA can be used again for further translation and the polypeptide chain can go off for some more processing to be made into a protein. The rate at which transcription and translation occur drive evolution, along with the chosen alternative splicing of the messenger RNA. As new genes are expressed and frequently expressed, new proteins are made and new adaptations and traits can be seen in the species. Natural selection then can work on these different variants and the species becomes stronger and survives longer. Translation The second major step in gene expression is called translation. After the messenger RNA makes a complementary strand to a single strand of DNA in transcription, it then gets processed during RNA splicing and is then ready for translation. Since the process of translation occurs in the cytoplasm of the cell, it has to first move out of the nucleus through the nuclear pores and out into the cytoplasm where it will encounter the ribosomes needed for translation. Ribosomes are an organelle within a cell that helps assemble proteins. Ribosomes are made up of ribosomal RNA and can either be free floating in the cytoplasm or bound to the endoplasmic reticulum making it rough endoplasmic reticulum. A ribosome has two subunits - a larger upper subunit and the smaller lower subunit. A strand of messenger RNA is held between the two subunits as it goes through the process of translation. The upper subunit of the ribosome has three binding sites called the â€Å"A†, â€Å"P† and â€Å"E† sites. These sites sit on top of the messenger RNA codon, or a three nucleotide sequence that codes for an amino acid. The amino acids are brought to the ribosome as an attachment to a transfer RNA molecule. The transfer RNA has an anti-codon, or complement of the messenger RNA codon, on one end and an amino acid that the codon specifies on the other end. The transfer RNA fits into the â€Å"A†, â€Å"P† and â€Å"E† sites as the polypeptide chain is built. The first stop for the transfer RNA is a â€Å"A† site. The â€Å"A† stands for aminoacyl-tRNA, or a transfer RNA molecule that has an amino acid attached to it. This is where the anti-codon on the transfer RNA meets up with the codon on the messenger RNA and binds to it. The ribosome then moves down and the transfer RNA is now within the â€Å"P† site of the ribosome. The â€Å"P† in this case stands for peptidyl-tRNA. In the â€Å"P† site, the amino acid from the transfer RNA gets attached via a peptide bond to the growing chain of amino acids making a polypeptide. At this point, the amino acid is no longer attached to the transfer RNA. Once the bonding is complete, the ribosome moves down once again and the transfer RNA is now in the â€Å"E† site, or the â€Å"exit† site and the transfer RNA leaves the ribosome and can find a free floating amino acid and be used again. Once the ribosome reaches the stop codon and the final amino acid has been attached to the long polypeptide chain, the ribosome subunits break apart and the messenger RNA strand is released along with the polypeptide. The messenger RNA may then go through translation again if more than one of the polypeptide chain is needed. The ribosome is also free to be reused. The polypeptide chain can then be put together with other polypeptides to create a fully functioning protein. The rate of translation and the amount of polypeptides created can drive evolution. If a messenger RNA strand is not translated right away, then its protein it codes for will not be expressed and can change the structure or function of an individual. Therefore, if many different proteins are translated and expressed, a species can evolve by expressing new genes that may not have been available in the gene pool before. Similarly, if an is not favorable, it may cause the gene to stop being expressed. This inhibition of the gene may occur by not transcribing the DNA region that codes for the protein, or it could happen by not translating the messenger RNA that was created during transcription.

Monday, November 4, 2019

The impcat of the drug culture on the Rock music industry of the 70's Research Paper

The impcat of the drug culture on the Rock music industry of the 70's - Research Paper Example se of the Soviet Union which effectively brought the Cold War to an end, creating a suitable condition for the society to thrive and prosper politically, economically and socio-culturally. Therefore, the drug culture emerged as a means of assuring stable and healthy living, through fighting diseases and illnesses that were commonly associated with the previous war periods, to give people more freedom to enjoy life (). Thus, many drugs were invented to play different roles, with some targeted at preventing and curing diseases, while others were meant to keep people alert, help people sleep, to lessen their worry and anxiety and alleviate pain (). Therefore, the availability of all sorts of drugs created a wave of optimism in the 1970s society, effectively impacting on the rest of the socio-cultural aspects of the society such as the lifestyles and the music development. This way, songs were written and sang about a variety of drugs, especially those drugs that provoked societal resist ance such as the hard drugs including cocaine, heroin and marijuana (). These drugs were being resisted by the society owing to their addictive and negative health implications on individuals’ mental and psychological health, yet they were perceived to offer the rest of the drug benefits such as keeping people alert making them feel high and good about themselves, as well as reducing sensitivity and increasing creativity. The influence of such drugs made artists feel inspired, while also removing the inhibitions that would disrupt performance such as tiredness, thus helping to keep the party moving (). Therefore, the influence of the drug culture was the formation of the creation of soundtracks of roll and roll to promote a revolution of celebrating drugs, and the consequent stability, peace and the joy of love and sex that came with the drug culture, in a society that was defined by obsession with wars (). In this respect therefore, the drug culture helped o promote the rock and roll

Saturday, November 2, 2019

I have an article need to be reviewed Example | Topics and Well Written Essays - 1000 words

I have an need to be reviewed - Article Example Chris Howell has a Doctor of Philosophy from Yale University, while Rebecca Kolins Gavin has a doctorate in Political Science from Northwestern University. Their work has been cited 14 times since it was published in 2011. Comparative political economy claims that institutions are important because they mediate economic pressures, distribute powers among actors, and offers solutions to problems that are faced by market economies (Hall & Taylor 1996). The authors have focused on the political economic approach, developed by Frege and Kelly (2013), in which the focus is on the historical and institutional roots of employment regimes and institutions. They have described in detail the role of the state in the development of industrial relations in all three countries, but have given limited description about the role of the market factors in these events. The Varieties of Capitalism (VOC) model (Hall & Soskice 2001) has been used to try to understand and compare the patterns of industrial relations and institutional changes in the three countries. It is mentioned in the article that institutions are not able to perform in isolation, and that there will be interactions and complementarities between them as suggested by the VOC model. The Dunlop system theory has assumed that common technologies and cross-national markets would create convergence towards a common model of employment regulation. A feature of the period since the mid-1980s can support this claim where it can be observed that even though there have been differences in the policies and details accompanying reform, the direction of institutional change has been broadly similar across governments of different political natures. However, it also assumes that the market factors and employers are the main factors, while politics and the government are just secondary forces.